Brown 1994.
Methods | RCT Approved by the local Ethics Committee and signed written informed consent from each participant |
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Participants | Orthopaedic hospital in Hong Kong 20 ASA 2 or 3 patients with a proximal femoral fracture Mean age 77 years (range 66‐91) Male: 50% Number lost to follow‐up: not stated | |
Interventions | Premedication with pethidine or temazepam Treatment group: Spinal (subarachnoid) anaesthesia with 0.2 mg/kg hyperbaric bupivacaine (n = 10) Control group: General anaesthesia using thiopentone or propofol, isoflurane or enflurane atracurium and nitrous oxide/oxygen (n= 10) |
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Outcomes | Operative hypotension (requiring administration of vasopressor) | |
Notes | Length of follow‐up: 2 days (up to 44 hours) | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Randomized trial: use of random numbers table |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up |
Selective reporting (reporting bias) | Low risk | No failed neuraxial block mentioned |
Other bias | Low risk | Groups well balanced |