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. 2016 Feb 22;2016(2):CD000521. doi: 10.1002/14651858.CD000521.pub3

Messina 2013.

Methods RCT
Approved by the Ethics Committee
Participants Patients > 75 years of age admitted with fractured hips not scheduled for hip replacement
Interventions Treatment group: Spinal with 7.5 mg of levobupivacaine plus 5 mcg of sufentanil performed in the lateral position with the fractured side uppermost. Patients were kept in this position for 5 minutes (n = 10)
Control group: General anaesthesia with propofol, sevoflurane, remifentanil and cisatracurium (n = 10)
All patients received Ringer's Lactate solution 500 mL rapidly administered via the peripheral line before either spinal or general anaesthesia induction, Voluven", (hydroxyethylstarch 6%), 20 mL X BMI l3 was used to treat the first episode of hypotension in both groups
Outcomes Surgery (min)
Operative hypotension (MAP decrease of 25% or more)
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated randomization list
Allocation concealment (selection bias) Unclear risk Not mentioned
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not mentioned
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Not mentioned
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No loss to follow‐up
Selective reporting (reporting bias) Low risk No failed spinal mentioned: "All patients in subarachnoid anaesthesia group had an effective intraoperative anaesthesia and analgesia"
Other bias Low risk Groups well balanced