Messina 2013.
Methods | RCT Approved by the Ethics Committee |
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Participants | Patients > 75 years of age admitted with fractured hips not scheduled for hip replacement | |
Interventions |
Treatment group: Spinal with 7.5 mg of levobupivacaine plus 5 mcg of sufentanil performed in the lateral position with the fractured side uppermost. Patients were kept in this position for 5 minutes (n = 10) Control group: General anaesthesia with propofol, sevoflurane, remifentanil and cisatracurium (n = 10) All patients received Ringer's Lactate solution 500 mL rapidly administered via the peripheral line before either spinal or general anaesthesia induction, Voluven", (hydroxyethylstarch 6%), 20 mL X BMI l3 was used to treat the first episode of hypotension in both groups |
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Outcomes | Surgery (min) Operative hypotension (MAP decrease of 25% or more) |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Computer‐generated randomization list |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up |
Selective reporting (reporting bias) | Low risk | No failed spinal mentioned: "All patients in subarachnoid anaesthesia group had an effective intraoperative anaesthesia and analgesia" |
Other bias | Low risk | Groups well balanced |