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. 2016 Feb 22;2016(2):CD000521. doi: 10.1002/14651858.CD000521.pub3

Racle 1986.

Methods RCT
Consent obtained from the family or the patient for the spinal anaesthesia group
Participants Orthopaedic hospital in Cedex, France
 70 female patients with a proximal femoral fracture
 Mean age: 82 years (Inclusion criterion: 75+, range not given)
 Male: 0%
 Number lost to follow‐up: not state
Hemi‐ or total hip arthroplasty
Interventions Premedication with IM hydroxyzine and atropine
Treatment group: 200‐300 IV fluids before the spinal and 8 mL/kg after. Spinal anaesthesia with 3 mL 0.5% bupivacaine + adrenaline with the patients lying on the fractured side (n = 35). Flunitrazepam for sedation
 Control group: General anaesthesia using thiopentone, vecuronium, fentanyl, nitrous oxide/oxygen, enflurane (n = 35)
Outcomes Mortality at 1 and 3 months
 Length of surgery
 Operative hypotension (number of patients with > 20% decrease in systolic arterial blood pressure)
 Length of hospital stay
 Pneumonia
Congestive cardiac failure
 Acute confusional state (maximal number observed)
Pulmonary embolism
Acute kidney injury
Cerebrovascular accident
Notes Length of follow‐up: 3 months
In French
Early mobilization and heparin for thromboprophylaxis
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "Randomization table Cochran and Cox"
Allocation concealment (selection bias) Unclear risk Not mentioned
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not mentioned
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Not mentioned
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No loss to follow‐up
Selective reporting (reporting bias) Low risk No failed spinal
Other bias Low risk Groups well balanced