Racle 1986.
Methods | RCT Consent obtained from the family or the patient for the spinal anaesthesia group |
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Participants | Orthopaedic hospital in Cedex, France
70 female patients with a proximal femoral fracture
Mean age: 82 years (Inclusion criterion: 75+, range not given)
Male: 0%
Number lost to follow‐up: not state Hemi‐ or total hip arthroplasty |
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Interventions | Premedication with IM hydroxyzine and atropine Treatment group: 200‐300 IV fluids before the spinal and 8 mL/kg after. Spinal anaesthesia with 3 mL 0.5% bupivacaine + adrenaline with the patients lying on the fractured side (n = 35). Flunitrazepam for sedation Control group: General anaesthesia using thiopentone, vecuronium, fentanyl, nitrous oxide/oxygen, enflurane (n = 35) |
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Outcomes | Mortality at 1 and 3 months
Length of surgery
Operative hypotension (number of patients with > 20% decrease in systolic arterial blood pressure)
Length of hospital stay
Pneumonia Congestive cardiac failure Acute confusional state (maximal number observed) Pulmonary embolism Acute kidney injury Cerebrovascular accident |
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Notes | Length of follow‐up: 3 months In French Early mobilization and heparin for thromboprophylaxis |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "Randomization table Cochran and Cox" |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up |
Selective reporting (reporting bias) | Low risk | No failed spinal |
Other bias | Low risk | Groups well balanced |