Table 1. The comparison of demographics, anthropometric factors and laboratory findings between young healthy male adults with and without family history of premature coronary artery disease.

Variable		Total sample	Family history of P-CAD		p-value
			With	Without
N (%)		411 (100)	223 (54.3)	188 (45.7)
Age [years]		28.5 ± 4.3	28.8 ± 4.5	28.0 ± 4.0	0.03
Current vs. never and former smoking (%)		103 (25.1)	71 (31.8)	32 (17.0)	0.0009
Physical examination
	BMI [kg/m2]	25.9 ± 4.0	26.6 ± 4.0	24.9 ± 3.8	<0.0001
	WHR	0.89 ± 0.09	0.91 ± 0.08	0.87 ± 0.08	<0.0001
	SBP [mmHg]	131.2 ± 14.1	131.0 ± 13.8	131.4 ± 14.5	0.72
	DBP [mmHg]	80.0 ± 11.0	79.5 ± 11.5	80.6 ± 10.4	0.47
Laboratory test results
	Cholesterol [mmol/L]	5.1 ± 1.2	5.2 ± 1.2	4.9 ± 1.1	0.005
	LDL-C [mmol/L]	3.2 ± 1.0	3.4 ± 1.0	3.0 ± 0.9	<0.0001
	Apolipoprotein B [g/L]	1.0 ± 0.3	1.01± 0.29	0.96 ± 0.29	0.08
	HDL-C [mmol/L]	1.4 ± 0.4	1.4 ± 0.4	1.5 ± 0.4	0.13
	Apolipoprotein A1 [g/L]	1.5 ± 0.3	1.5 ± 0.2	1.5 ± 0.3	0.27
	HDL [%] Triglycerides [mmol/L]	29.2 ± 9.5 1.4 ± 1.4	27.9 ± 9.4 1.5 ± 1.6	30.7 ± 9.5 1.2 ± 1.1	0.002 0.03
	Lp(a) [nmol/L]	42.8 ± 66.2	49.9 ± 72.7	34.5 ± 56.6	0.03
	Uric acid [μmol/L]	349.8 ± 66.5	352.3 ± 65.3	346.8 ± 67.8	0.41
	Albumin [g/L]	48.6 ± 2.5	48.3 ± 2.5	48.9 ± 2.5	0.03
	hsCRP [mg/dl]	1.3 ± 1.3	1.4 ± 1.4	1.2 ±1.2	0.08
	Glucose [mmol/l]	5.1 ± 0.5	5.2 ± 0.4	5.0 ± 0.5	<0.0001
	HbA1c [%]	5.05 ± 0.26	5.11 ± 0.25	4.97 ± 0.25	<0.0001
	Fibrinogen [mg/dL]	263.9 ± 58.0	271.7 ± 52.8	254.6 ± 62.5	<0.0001

Abbreviations: BMI–body mass index; DBP–diastolic blood pressure; HDL-C–high-density lipoprotein cholesterol; hsCRP–high-sensitivity C-reactive protein; LDL-C–low-density lipoprotein cholesterol; Lp(a)–lipoprotein(a); P-CAD–premature coronary artery disease; WHR–waist-to-hip ratio.