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. 2017 Mar 31;2017(3):CD001292. doi: 10.1002/14651858.CD001292.pub3

Chen 2014.

Methods Study design: Randomied controlled trial
Setting: Hospital, China
Recruitment: community volunteers and referrals from outpatient clinics
Participants 190 smokers, > 1 cpd, 97% men, av.age 50, av. cpd 20. All had lung function tests; 85 had COPD and 105 were asymptomatic
Interventions Therapist: "Interventions provided by 2 doctors with experience of professional smoking cessation treatment."
1. Cognitive counselling, 20 mins at baseline and 9 calls > 10 mins at 1 ‐ 4 wks, 6 wks, 8 wks, 3 ‐ 5 m. S‐H materials
2. Brief advice
Outcomes Abstinence at 6 m sustained from week 4
Validation: CO < 10 ppm
Notes New for 2016 update
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "assigned to the intervention or control group according to the randomized digital table" stratified by motivation to quit
Allocation concealment (selection bias) Unclear risk No further details
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Biochemical validation of abstinence
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 12 withdrawals included as smokers