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. 2017 Mar 31;2017(3):CD001292. doi: 10.1002/14651858.CD001292.pub3

Cropsey 2015.

Methods Study design: Randomized controlled trial
Setting: Community corrections facility, USA
Recruitment: smokers under community corrections supervision
Participants 500 smokers; 33% women; av. age 37.4; av. cpd 17.9
Interventions Therapist: Clincal psychologist
1. Control. Brief physician advice to set TQD 1 ‐ 2 wks after starting bupropion, stressed adherence
2. Intervention. As 1. plus 4 x 20 ‐ 30‐min counselling sessions; cognitive and behavioural strategies
Pharmacotherapy: All participants received bupropion for 12 wks
Outcomes Abstinence at 12 m (PP)
Validation: CO ≤ 3 ppm at all visits
Notes New for 2016 update
Paper reports differential abstinence by race. Author confirmed quit rates in Fig 2, used to calculate numbers quit
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomized, blocked on race, no further details
Allocation concealment (selection bias) Unclear risk No details given
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Biochemical validation of abstinence
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 23% I, 26% C lost to follow‐up