Cropsey 2015.
Methods | Study design: Randomized controlled trial Setting: Community corrections facility, USA Recruitment: smokers under community corrections supervision |
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Participants | 500 smokers; 33% women; av. age 37.4; av. cpd 17.9 | |
Interventions | Therapist: Clincal psychologist 1. Control. Brief physician advice to set TQD 1 ‐ 2 wks after starting bupropion, stressed adherence 2. Intervention. As 1. plus 4 x 20 ‐ 30‐min counselling sessions; cognitive and behavioural strategies Pharmacotherapy: All participants received bupropion for 12 wks |
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Outcomes | Abstinence at 12 m (PP) Validation: CO ≤ 3 ppm at all visits |
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Notes | New for 2016 update Paper reports differential abstinence by race. Author confirmed quit rates in Fig 2, used to calculate numbers quit |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomized, blocked on race, no further details |
Allocation concealment (selection bias) | Unclear risk | No details given |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Biochemical validation of abstinence |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 23% I, 26% C lost to follow‐up |