Schmitz 1999.

Methods	Study design: Randomized controlled trial Setting: Hospital, USA Recruitment: women with or at risk of CAD
Participants	2 separate samples recruited: 53 inpatients with CAD who stopped smoking during hospitalization and wanted to stay quit 107 women volunteering for cessation treatment who had > 1 CAD risk factor
Interventions	Therapists: 2 smoking counsellors + 2 clinical psychology interns 1. Coping skills, relapse prevention, 6 x 1‐hr including stress management, homework 2. Health Belief model, 6 x 1‐hr, smoking‐related health information about disease state or CAD profile Focus on benefits of stopping
Outcomes	Abstinence at 6 m (PP) Validation: CO < 9 ppm, urine cotinine < 10 ng/ml Not all quitters tested, confirmation rates not reported
Notes	Post‐randomization dropouts who did not complete baseline and begin treatment were not included in any data Quit rates were lower in the CAD sample than in the at‐risk group
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Randomly assigned", stratified on smoking rate and myocardial infarction status
Allocation concealment (selection bias)	Unclear risk	No details given
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Some validation of abstinence, arms had similar intensities of treatment
Incomplete outcome data (attrition bias) All outcomes	Low risk	Pretreatment dropouts were excluded, all others included in ITT analysis