Xiao 2008.
Methods | Randomised clinical trial with 2 arms: three dimensional conformal radiotherapy (3‐DCRT) plus transarterial chemoembolisation (TACE) versus TACE. Parallel‐group design | |
Participants | 60 people with unresectable primary hepatic carcinoma. TACE + 3‐DCRT = 30; TACE = 30 Median age: not reported Male/female: 45/15 Recruitment: January 2002 to June 2006 Inclusion criteria: Chinese Medical Association guideline:
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Interventions | TACE: femoral artery by Seldinger technique 3‐DCRT: total average dose = 55 Gy |
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Outcomes |
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Notes | Country of the study: China We were unable to make a contact with the corresponding author to request missing data. Funding: unclear |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Allocation sequence was generated by random table number. |
Allocation concealment (selection bias) | Unclear risk | The method used to conceal the allocation was not described. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | The trial was not blinded, so that the allocation was known during the trial. |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Outcome was assessed by apparatus. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | There were insufficient data to assess attrition bias. |
Selective reporting (reporting bias) | High risk | The study did not report cancer‐related mortality, quality of life, or serious adverse events. |
For profit bias | Unclear risk | Unclear funding source. |
Other bias | Unclear risk | Unclear risk of other bias. |