Table 2:
Multivariate analysis of overall survival for women with metastatic breast cancer
| Predictors | Total mbc cohort (N=6539) | |
|---|---|---|
| Hazard ratio | 95% CI | |
| Ethnicity1 (reference = Caucasian) | ||
| African American | 1.84 | 1.39–2.45 |
| Mixed | 1.04 | 0.86–1.26 |
| Age-at-diagnose (reference = 50 – 64 years) | ||
| 25 – 40 years | 0.85 | 0.67–1.07 |
| 40 – 49 years | 0.89 | 0.77–1.03 |
| Socio-economic status2 (reference = high SES) | ||
| Low SES | 1.05 | 0.90–1.23 |
| Morbidity3 (reference = low morbidity) | ||
| High morbidity | 1.30 | 1.12–1.51 |
| Geographic region (reference = South) | ||
| West | 1.20 | 0.97–1.48 |
| Midwest | 0.95 | 0.81–1.11 |
| Northeast | 0.73 | 0.56–0.95 |
| Urban / non-urban4 (reference = urban areas) | ||
| Non-urban areas | 1.09 | 0.94–1.26 |
| Year of diagnosis (reference = 2005–2008) | ||
| 2000–2004 | 1.60 | 1.39–1.83 |
Bold means significant p = <0.05
African American: residing in predominantly African American (≥ 66%) neighborhoods
Caucasian: residing in predominantly Causasian (≥ 66%) neighborhoods
Mixed = women with Hispanic or Asian surname as well as women residing in predominantly mixed neighborhoods
Low SES: > 25% only HS education or > 10% below poverty
High SES: <25% only HS education or <10% below poverty
Very high morbidity: ACG score > 3.0
Low morbidity: ACG score 0 – 3.0
Non-urban: all remaining categories 2 – 12
Urban: large metropolitan area of 1+ million residents [36]
ACG = Adjusted Clinical Groups, HS = high school, mbc = metastatic breast cancer, SES = socioeconomic status