Chen 2013.

Methods	Two‐arm single centre randomized study
Participants	124 critically ill patients admitted to Department of Critical Care Medicine of Jiangxi Provincial People's Hospital from 1 May 2012 to 30 April 2013 needing mechanical ventilation. More Inclusion criteria: APACHE II > 15, at risk for IFI Exclusion criteria: patients with IFI, length of stay in ICU < 3 days, patients receiving antifungal drugs, allergy to antifungal drugs
Interventions	One group received placebo (gastrointestinal prokinetic drug) Another group received nystatin 1000 kU three times a day via the gastric tube
Outcomes	Candida colonization (Corrected colonization index) Incidence of candidaemia ICU stay Mortality
Notes	We could not know the percentage of included neutropenic patients or treated with immunosuppressive therapy (information was recorded by the investigators but not reported) PubMed: 24021043 Contact: Zeng Jun, Department of Critical Care Medicine, People's Hospital of Jiangxi Province, Nanchang 330006, Jiangxi, China. Corresponding author: Zeng Jun, Email: Katherine‐cjl@163.com