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. 2016 Jan 16;2016(1):CD004920. doi: 10.1002/14651858.CD004920.pub3

Whitby 2005.

Methods Two‐arm single centre randomized controlled study
Participants Males and females with highly suspected or confirmed invasive fungal infection. Patients' clinical characteristics not stated
Interventions Liposomal amphotericin B or conventional amphotericin B for a minimum of 14 days. Salvage therapy (AmBisome 5 mg/kg/day). Total duration of therapy depends on the infection and the patient's condition
Outcomes Primary outcome: rate of treatment‐related adverse events
Secondary outcome: Microbiological & Clinical Evaluation measured during double blind period and rescue period
Notes Target sample size: 104. Recruitment status: completed.
Contact: Michael Whitby, Infectious Diseases Department, Princess Alexandra Hospital, Ipswich Rd, Woolloongabba, QLD, Australia

APACHE = acute physiology and chronic health evaluation

Cfu = colony forming units

CI = colonization index

ICU = intensive care unit

IFI = invasive fungal infection

kU = kilounits

RSS = risk severity score