NCT02471573

Trial name or title	Freeze all protocol versus fresh embryo transfer in women undergoing in‐vitro fertilization (IVF)
Methods	RCT Estimated enrolment: 780
Participants	Women aged 18 to 42 Inclusion criteria: Undergoing IVF treatment Number of previously failed embryo transfers ≤ 2 Permanent living in Vietnam Ovarian hyperstimulation with GnRH antagonist protocol Eligible for embryo transfer on day 3 Having at least 1 top‐quality embryo on day 3 Number of embryos transferred ≤ 2 Willing to participate in the study Not concurrently participating in another IVF study Exclusion criteria: In vitro maturation cycles Oocyte donation cycles Using GnRH agonist for triggering
Interventions	Freeze‐all protocol: Embryos are selected for cryopreservation using vitrification technique. 2 vitrified embryos will be warmed and transferred in subsequent cycle. Fresh transfer protocol: 2 embryos are selected and transferred fresh in the same cycle.
Outcomes	Live birth: a live newborn delivered Ongoing pregnancy: a pregnancy with positive heartbeat beyond 12 weeks of gestation Clinical pregnancy: presence of a gestational sac seen by transvaginal sonography 7 weeks after embryo placement Multiple pregnancy: 2 or more foetal heart rates by transvaginal sonography 7 weeks after embryo placement
Starting date	June 2015
Contact information	Lan TN Vuong: drlan@yahoo.com.vn Vinh Q Dang: bsvinh.dq@myduchospital.vn
Notes	clinicaltrials.gov/ct2/show/record/NCT02471573