Comparison 2. Partial bed rest in hospital versus no activity restriction at home.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Very preterm birth (less than 34 weeks) ‐ assuming complete correlation between twins	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	2.30 [0.84, 6.27]
2 Perinatal mortality	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 Assuming independence between twins	1	282	Risk Ratio (M‐H, Fixed, 95% CI)	4.17 [0.90, 19.31]
2.2 Assuming complete correlation between twins	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	4.17 [0.48, 36.42]
3 Prelabour preterm rupture of the membrane	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	1.51 [0.69, 3.30]
4 Spontaneous onset of labour	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	1.03 [0.89, 1.18]
5 Caesarean delivery	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	1.10 [0.81, 1.49]
6 Development of maternal hypertension	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	0.30 [0.16, 0.59]
7 Stillbirth (after 20 weeks and before birth)	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
7.1 Assuming independence between twins	1	282	Risk Ratio (M‐H, Fixed, 95% CI)	5.22 [0.62, 44.09]
7.2 Assuming complete correlation between twins	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	3.13 [0.33, 29.37]
8 Early neonatal death (within 7 days after birth)	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
8.1 Assuming independence between twins	1	282	Risk Ratio (M‐H, Fixed, 95% CI)	3.13 [0.33, 29.73]
8.2 Assuming complete correlation between twins	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	2.09 [0.19, 22.50]
9 Preterm birth (less than 37 weeks) ‐ assuming complete correlation between twins	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.79, 1.46]
10 Birthweight twin I (g)	1	141	Mean Difference (IV, Fixed, 95% CI)	‐90.0 [‐299.40, 119.40]
11 Birthweight twin II (g)	1	141	Mean Difference (IV, Fixed, 95% CI)	‐80.0 [‐294.84, 134.84]
12 Very low birthweight (less than 1500 g)	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
12.1 Assuming independence between twins	1	282	Risk Ratio (M‐H, Fixed, 95% CI)	1.74 [0.88, 3.42]
12.2 Assuming complete correlation between twins	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	1.74 [0.67, 4.53]
13 Gestational age at delivery (weeks)	1	141	Mean Difference (IV, Fixed, 95% CI)	‐0.60 [‐1.56, 0.36]
14 Small‐for‐gestational age	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
14.1 Assuming independence between twins	1	282	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.69, 1.26]
14.2 Assuming complete correlation between twins	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.61, 1.43]
15 Apgar score less than 7 for twin I (at 5 minutes)	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	2.09 [0.19, 22.50]
16 Apgar score less than 7 for twin II (at 5 minutes)	1	141	Risk Ratio (M‐H, Fixed, 95% CI)	2.09 [0.39, 11.03]