Comparison 2. Glue versus suture: worst case scenarios.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Chronic pain	10	1473	Odds Ratio (M‐H, Fixed, 95% CI)	0.65 [0.46, 0.91]
1.1 Synthetic glue versus suture	7	945	Odds Ratio (M‐H, Fixed, 95% CI)	0.69 [0.47, 1.02]
1.2 Biological glue versus suture	3	528	Odds Ratio (M‐H, Fixed, 95% CI)	0.53 [0.27, 1.05]
2 Hernia recurrence	12	1987	Odds Ratio (M‐H, Fixed, 95% CI)	1.22 [0.80, 1.85]
2.1 Synthetic glue versus suture	8	991	Odds Ratio (M‐H, Fixed, 95% CI)	1.31 [0.84, 2.04]
2.2 Biological glue versus suture	4	996	Odds Ratio (M‐H, Fixed, 95% CI)	0.67 [0.19, 2.40]