| Study | Reason for exclusion |
|---|---|
| Barillari 1996 | 607 participants were enrolled in this trial; 212 were randomised, but the trial did not report data for these randomised participants separately. |
| Kronborg 1981 | This was a prospective, partly randomised trial. We were unable to extract the data relating to randomised participants from the paper. |
| Sano 2004 | The study was ineligible; participants had not had colorectal cancer. |
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