Wenisch 2014.

Methods	STUDY DESIGN: ITS Risk of Bias: LOW
Participants	PROVIDERS: all physicians in the hospital PARTICIPANTS: all patients in the hospital CLINICAL PROBLEM: patients receiving moxifloxacin SETTING: 1 university hospital in Austria
Interventions	FORMAT: Intervention: educational meetings; restrictive by compulsory order form Intervention Functions: education, restriction DELIVERER: AMT COMPARISON: usual care DESIRED CHANGE: decrease excessive
Outcomes	PRESCRIBING: Choice: use of moxifloxacin in DDD
Notes	FINANCIAL SUPPORT: no information ADDITIONAL DATA: no response from authors to request for additional data Microbial Risk of Bias: Low for case definition, planned intervention, and other infection control
Risk of bias
Bias	Authors' judgement	Support for judgement
Intervention independent (ITS) ?	Low risk
Analysed appropriately (ITS) ?	Low risk	Re‐analysed
Shape of effect pre‐specified (ITS) ?	Low risk	Point of intervention was point of analysis.
Unlikely to affect data collection (ITS) ?	Low risk	Data from pharmacy and microbiology computers
Knowledge of the allocation adequately prevented(ITS)?	Low risk	Data from pharmacy and microbiology computers
Incomplete outcome data addressed (ITS) ?	Low risk	Data from pharmacy and microbiology computers
Free of selected reporting (ITS) ?	Low risk	Data from pharmacy and microbiology computers
Free of other bias (ITS) ?	High risk	< 12 months' data in the pre‐intervention (5 months) and postintervention (7 months) phases Microbial Risk of Bias LOW: case definition Low, planned intervention Low, other infection control Low