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. 2017 Feb 4;2017(2):CD010331. doi: 10.1002/14651858.CD010331.pub2

Comparison 2. Amethocaine versus placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Pain 1 110 Mean Difference (IV, Fixed, 95% CI) ‐5.0 [‐17.34, 7.34]
2 Successful cannulation first attempt 1 39 Risk Ratio (M‐H, Fixed, 95% CI) 1.21 [0.82, 1.81]
3 Adverse effects 3 181 Risk Ratio (M‐H, Fixed, 95% CI) 2.0 [0.64, 6.26]