Rein 1996.

Methods	Randomised controlled trial
Participants	Women undergoing IVF cycles; 25 women participated, 34 cycles
Interventions	0.5 of dexamethasone versus placebo
Outcomes	number of follicles >12 mm in diameter serum oestradiol concentrations on the day of hCG administration number of ampoules of HMG administered number of oocytes retrieved percentage of oocytes fertilised number of embryos transferred implantation rate numbers of clinical pregnancies and live birth pregnancies
Notes	Data per cycle not per woman; no response to our requests for per woman data.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"The randomization scheme was based on computer‐generated permuted blocks ..."
Allocation concealment (selection bias)	Low risk	"Compliance with the study medications was confirmed by our nurse coordinator"
Blinding of participants and personnel (performance bias) All outcomes	Low risk	"The clinical investigators and patients remained blinded to the treatment group throughout the duration of the study"
Blinding of outcome assessment (detection bias) All outcomes	Low risk	"The clinical investigators and patients remained blinded to the treatment group throughout the duration of the study"
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Could not get the necessary data from the trial author
Selective reporting (reporting bias)	Unclear risk	Could not get the necessary information from the trial author
Other bias	Unclear risk	Nine patients undergoing a subsequent IVF cycle were crossed over to the other treatment group (unclear how many from each group).

ICSI: intra‐cytoplasmic sperm injection
 IVF: in‐vitro fertilisation
 hCG: human chorionic gonadotropin
 HMG: human menopausal gonadotropins
 OHSS: ovarian hyperstimulation syndrome
 PCOS: polycystic ovarian syndrome