| Study | Reason for exclusion |
|---|---|
| Abuhamad 1999 | This abstract compares TRH + betamethasone with betamethasone + placebo. |
| Althabe 2015 | This is a trial of strategies to optimise use of corticosteroids. |
| Asnafei 2004 | This study is quasi‐experimental. |
| Butterfill 1979 | Randomised participants are combined with a non‐randomised cohort and cannot be analysed separately. |
| Dola 1997 | This abstract compares TRH + betamethasone with betamethasone + placebo. |
| Egerman 1998 | This trial compares oral vs IM dexamethasone in the prevention of RDS. It does not meet our entry criteria for inclusion of studies for the review. |
| Garite 1981 | This trial compares a policy of corticosteroid therapy followed by elective delivery with a policy of withholding corticosteroids and awaiting delivery so the independent effect of the 2 co‐interventions cannot be evaluated separately. |
| Grgic 2003 | Not a randomised trial. Outcomes for women who received steroids were compared with those that did not. Information obtained from translation sheet. Original article in Bosnian |
| Halac 1990 | Not a randomised trial. Women were allocated to placebo if they were expected to deliver within 24 h and to betamethasone if labour was not expected within 24 h. |
| Iams 1985 | Corticosteroid therapy (hydrocortisone) and co‐intervention of elective delivery was compared to expectant management in PROM. The independent effect of the 2 co‐interventions cannot be evaluated separately. |
| Khandelwal 2012 | Compared different doses of corticosteroid: 12‐hourly vs 24‐hourly. The study includes a repeat dose of corticosteroids and is eligible for inclusion in a different review, 'Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes' Crowther 2015. |
| Koivisto 2007 | The study includes a repeat dose of corticosteroids and is eligible for inclusion in a different review, 'Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes' Crowther 2015. |
| Kuhn 1982 | Randomised participants are combined with a non‐randomised cohort and cannot be analysed separately. |
| Kurtzman 2008 | The study includes a repeat dose of corticosteroids and is eligible for inclusion in a different review, 'Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes' Crowther 2015. |
| Liu 2006 | Quasi‐randomised study that allocated women according to the in‐patient sequence. Compared the effect of dexamethasone combined with vitamin K, dexamethasone alone and no dexamethasone or vitamin K on periventricular/intraventricular haemorrhage. |
| Magee 1997 | This study compares the effects of betamethasone vs dexamethasone on antenatal fetal heart rate. |
| Maksic 2008 | This study appears to be an observational study of 163 premature infants, 80 of whom were exposed to antenatal corticosteroids, and 83 of whom were not. |
| McEvoy 2010 | This trial compares repeat dose corticosteroids and is eligible for inclusion a different review, 'Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes' Crowther 2015. |
| Minoui 1998 | This study compares the effects of betamethasone vs dexamethasone on antenatal fetal heart rate. |
| Morales 1986 | Quasi‐randomised using medical record number. |
| Morrison 1978 | This study was included in original review. It is excluded from this update because of > 20% post‐randomisation exclusions and the fact that it was possibly quasi‐randomised. |
| Mulder 1997 | This study compares the effects of betamethasone vs dexamethasone on antenatal fetal heart rate. |
| Papageorgiou 1979 | This study was included in original review. It is excluded from this update because of > 20% post‐randomisation exclusions. Of 146 babies included in the study, the paper only reports outcomes for 61. |
| Romejko‐Wolniewicz 2013 | This is a head‐to‐head trial of 2 different regimens and is eligible for the Cochrane review entitled 'Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth' Brownfoot 2013. |
| Rotmensch 1999 | This study compares the effects of betamethasone vs dexamethasone on antenatal fetal heart rate. |
| Schmidt 1984 | This study was included in original review. It is excluded from this update because of > 20% post‐randomisation exclusions. The paper only reports results from 92 of 144 randomised mothers and 97 of 149 randomised babies. |
| Simpson 1985 | Quasi‐randomised study. Randomised participants are combined with a non‐randomised cohort and cannot be analysed separately. |
| Whitt 1976 | This trial compares IM betamethasone with IV cortisol. It does not meet our entry criteria for inclusion of studies for the review. |
IM: intramuscular IV: intravenous PROM: premature rupture of membranes RDS: respiratory distress syndrome TRH: thyrotropin‐releasing hormone vs: versus