Jiang 2011

Methods	Setting: single centre in China. Design: open‐label, 2 arm, parallel RCT.
Participants	148 participants with FD diagnosis (Rome III) with normal OGD. Exclusions: NSAID users. HP not routinely tested.
Interventions	PPI: pantoprazole 40 mg/day. Prokinetic: mosapride 5 mg 3 times/day. Duration: 2 weeks.
Outcomes	Decrease overall symptoms scores of FD. Absolute difference in overall symptoms score decrease.
Notes	Chinese language. Funding not stated.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random number table used.
Allocation concealment (selection bias)	Unclear risk	No information provided.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open‐label, participants and personnel not blinded.
Blinding of outcome assessment (detection bias) All outcomes	High risk	Open‐label, outcome assessors not blinded.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up.
Selective reporting (reporting bias)	Low risk	Reported planned outcome data.
Other bias	Low risk	No other risk of bias identified.