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. 2017 Feb 14;2017(2):CD003032. doi: 10.1002/14651858.CD003032.pub3

Comparison 2.

Lamotrigine versus valproate

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Seizure free 4 Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
1.1 Seizure free at 1 month 2 Risk Ratio (M‐H, Fixed, 95% CI) 8.42 [2.77, 25.59]
1.2 Seizure free at 3 months 3 Risk Ratio (M‐H, Fixed, 95% CI) 1.64 [1.16, 2.31]
1.3 Seizure freedom at 6 months 1 Risk Ratio (M‐H, Fixed, 95% CI) 1.42 [0.88, 2.28]
1.4 Seizure free at 12 months 4 Risk Ratio (M‐H, Fixed, 95% CI) 1.67 [1.32, 2.11]
2 Normalization fo the EEG 1 Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected