Table 3.
Adverse effects on lamotrigine: number of participants experiencing each event
| Event | Frank 1999 | Coppola 2004 | Huang 2009 | Glauser 2013 |
| Abdominal pain | 5 | |||
| Headache | 2 | 2 | 14 | |
| Nausea | 3 | 2* | ||
| Vomiting | 2* | |||
| Poor appetite | 2 | 9 | ||
| Increased appetite | 1 | 10 | ||
| Diarrhoea | 2 | |||
| Dizziness | 3 | 5 | 5 | |
| Hyperkinesia | 2 | |||
| Hyperactivity | 12 | |||
| Attention problems | 11 | |||
| Hostility | 11 | |||
| Concentration decreased | 9 | |||
| Personality change | 10 | |||
| Sleep problem | 5 | |||
| Depression | 11 | |||
| Slow process speed | 7 | |||
| Memory problem | 8 | |||
| Apathy | 3 | |||
| Fatigue | 1 | 18 | ||
| Rash | 10 | 1 | 2 | 6 |
| Nervousness | 1 | |||
| Diplopia | 1 |
* Nausea, vomiting, or both
Numbers of individuals within each study undertaking lamotrigine: 15 (Frank 1999), 19 (Coppola 2004), 24 (Huang 2009), 146 (Glauser 2013a).