Study	Reason for exclusion
Aiach 1989	Low molecular weight heparin dosage was adjusted.
Albada 1989	The results from participants treated for venous thrombosis of the upper limb and for pulmonary embolism could not be distinguished from those of people with leg vein thrombosis, and the outcome was incompletely evaluated.
Banga 1993	This was a dose‐finding study.
Bratt 1985	Intravenous route of administration of low molecular weight heparin, and adjustments were made to dose for this treatment.
Bratt 1990	Low molecular weight heparin dosage was adjusted.
de Valk 1995	This was a dose‐finding study.
Handeland 1990	This was a dose‐finding study.
Harenberg 1989	Abstract with incomplete data.
Harenberg 1990	The results from people treated for venous thrombosis of the upper limb and for pulmonary embolism could not be distinguished from those of participants with leg vein thrombosis, and the outcome was incompletely evaluated.
Harenberg 2000b	Abstract with incomplete data.
Holm 1986	Low molecular weight heparin dosage was adjusted.
Kearon 2006	The administration of unfractionated heparin was not in adjusted dose.
Lockner 1985	Intravenous route of administration of low molecular weight heparin.
Lockner 1986	Intravenous route of administration of low molecular weight heparin.
Ly 1985	Adjustment of low molecular weight heparin dosages.
Monreal 1993	The 2 treatment strategies differ with respect to long‐term treatment.
Monreal 1994	The 2 treatment strategies differ with respect to long‐term treatment.
Notarbartolo 1988	Dosage of unfractionated heparin was not adjusted.
Quiros 2001	Not a randomised controlled trial.
Riess 2014	Substudy of Harenberg 1990 and Reiss 2003 studies which are already included in the review.
Siguret 2011	Comparison group were not treated with unfractionated heparin.
Stricker 1999	The main outcome of the study was the effect on haemostatic markers which is not within the scope of our review.
Tedoldi 1993	Dosage of unfractionated heparin was not adjusted.
Ucar 2015	Participants were given thrombolytic treatment.
Vogel 1987	Intravenous route of administration of low molecular weight heparin.
Zanghi 1988	Dosage of unfractionated heparin was not adjusted.