Wilkinson 2007.

Methods	Study design: RCT Study grouping: Parallel group
Participants	Baseline characteristics Exercise Number enrolled: 18 Age: unclear Type PH: unclear Control Number enrolled: 18 Age: unclear Type of PH: unclear Included criteria: "Clinically stable PH patients in a single centre" Excluded criteria: unclear
Interventions	Intervention characteristics Exercise Setting: outpatient, 3 months, 1 supervised session followed by unsupervised home training, telephone follow‐up "Best practice treatment plus a physiotherapist‐led rehabilitation programme (rehabilitation group). Patients in the rehabilitation group attended a single one to one class with a physiotherapist and received a prescribed set of exercises tailored to their needs. They also received telephone support during the 3 month period and were encouraged to continue with their regular exercise regime." Control "Best practice treatment"
Outcomes	Incremental shuttle walk test Endurance shuttle walk test Assessed at baseline and 3 months
Identification	Sponsorship source: Country: Setting: Comments: Author's name: Anna Wilkinson Institution: Royal Hallamshire Hospital Email: Address:
Notes	Reported as two abstracts In the Thorax abstract it does not specify the number in each group, only that 40 were randomised. ERS abstract says 18 in each group. Neither specifies age by allocated group
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Abstract only, does not specify how sequence was generated
Allocation concealment (selection bias)	Unclear risk	Abstract only, does not specify
Blinding of participants and personnel (performance bias) All outcomes	High risk	Not possible to blind participants to intervention
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Quote: "Blind assessment was undertaken pre intervention and following 3 months"
Incomplete outcome data (attrition bias) All outcomes	High risk	Dropouts unclear. 2007 abstract specifies 40 participants and 2008 abstract specifies 36 participants.
Selective reporting (reporting bias)	High risk	Abstract only, not all outcomes reported
Other bias	High risk	Abstract only

bpm: beats per minute; CAMPHOR: Cambridge Pulmonary Hypertension Outcome Review; CI: Cardiac Index; CPET: cardiopulmonary exercise test; CTEPH: chronic thromboembolitic pulmonary hypertension; Dual: patients on two pharmacotherapies; FEV1: forced expired volume in one second; FVC: forced vital capacity; HR: heart rate; HRQoL: health‐related quality of life; ITT: intention‐to‐treat; Mono: patients on single pharmacotherapy; mPAP: mean pulmonary artery pressure; NYHA: New York Heart Association; PAH: Pulmonary Artery Hypertension; PASP: Pulmonary Artery Systolic Pressure; PH: Pulmonary Hypertension, PLB: pursed lip breathing; PVR: pulmonary vascular resistance; RCT: randomised controlled trial; SF‐36: Short‐form 36; 6MWD: six minute walk distance; SPO₂: oxygen saturation; Triple: patients on 3 pharmacotherapies; QoL: quality of life; VO₂peak: peak oxygen uptake; W_peak: peak power