| Methods |
Randomised clinical trial |
| Participants |
Country: China.
Number randomised: 68.
Post‐randomisation drop‐outs: not stated.
Revised sample size: 68.
Average age: not stated.
Females: not stated.
NASH: not stated.
Diabetics: 68 (100%).
Average follow‐up period in months: 6.
Inclusion criteria
1. Patients with NAFLD and type 2 diabetes. |
| Interventions |
Participants were randomly assigned to four groups.
Group 1: sitagliptin (N = 17).
Further details: sitagliptin 100 mg/day.
Group 2: metformin (N = 17).
Further details: metformin 500 mg thrice daily.
Group 3: metformin and sitagliptin (N = 20).
Further details: metformin 500 mg thrice daily and sitagliptin 100 mg/day.
Group 4: control (N = 14).
Further details: control: no intervention.
Duration of treatment: 6 months. |
| Outcomes |
None of the outcomes of interest were reported in this trial. |
| Notes |
Reasons for post‐randomisation drop‐outs: not stated. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Quote: "Subjects were randomly divided into 4 groups". |
| Allocation concealment (selection bias) |
Unclear risk |
Comment: this information was not available. |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Quote: "open‐label". |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Quote: "open‐label". |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Comment: this information was not available. |
| Selective reporting (reporting bias) |
High risk |
Comment: protocol was not available; neither mortality nor adverse events were reported. |
| For‐profit bias |
Unclear risk |
Comment: this information was not available. |
| Other bias |
Low risk |
Comment: no other risk of bias. |
