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. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: J Immunol. 2016 Feb 17;196(6):2788–2798. doi: 10.4049/jimmunol.1502106

Fig. 7. Inhibition of JNK, p38, and NF-κB attenuates miR-146a-induced cfB gene expression.

Fig. 7

WT macrophages were pre-incubated with p38 inhibitor (SB203580, 20 μM), JNK inhibitor II (SP600125, 20 μM), ERK inhibitors (U0126, 10 μM; PD 98095, 20 μM), or NF-κB signaling inhibitor (Bay 11-7082,10 μM) for 1 hour prior to miR-146a (50 nM) or its U→A mutant treatment. cfB mRNA level was quantified by qRT-PCR 6 hours after treatment. * P < 0.05, δ P < 0.01, # P < 0.001, vs. corresponding mutant control. ** P < 0.01, *** P < 0.001. n=3 in each group.