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. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: Anal Chem. 2018 Aug 22;90(17):10472–10478. doi: 10.1021/acs.analchem.8b02463

Figure 1.

Figure 1.

(A) SolidWorks rendering of the home-built nESI-FT-DT-IM coupled to the HCD cell of an Orbitrap MS. (B) A detailed schematic representation of the home-built platform. From left to right depicts a heated capillary for ion introduction via nESI (not pictured) and an RF ion funnel to focus ions into the gating region. Ions are injected via gate 1 into a 58 cm PF DT and selectively transmitted through gate 2 into an RF-only octupole ion guide. Mobility modulated ions are then loaded and trapped in the HCD cell of the Orbitrap, where they are subsequently transferred to the C-Trap and then injected into the Orbitrap for mass analysis.