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. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: Anal Chem. 2018 Aug 22;90(17):10472–10478. doi: 10.1021/acs.analchem.8b02463

Figure 5.

Figure 5.

(A) Representative mass spectrum of the [M + 14H+]14+ TTR complex with binding of up to two T4 and Zn(II). A mass resolving power of 840 is required to separate the apo-Zn containing ions with the Orbitrap. (B) The extracted ATDs of TTR binding to one and two T4’s. (C) The extracted ATDs of TTR bound to Zn(II).