Table 2:
Spearman correlations between trauma severity and key sociodemographic, mental, and physical health variables in the study participants with and without schizophrenia
| Non-psychiatric participants Total CTQ score |
Schizophrenia Total CTQ score |
Test for equal correlations |
||||||
|---|---|---|---|---|---|---|---|---|
| r | p | N | r | p | N | z | p | |
| Sociodemographic | ||||||||
| Age at visit | 0.071 | 0.48 | 99 | −0.039 | 0.68 | 114 | 0.79 | 0.21 |
| Education (years) | −0.187 | 0.06 | 99 | −0.101 | 0.29 | 114 | −0.63 | 0.27 |
| Psychopathology | ||||||||
| Duration of Illness | 0.13 | 0.18 | 111 | |||||
| Antipsychotic dose (mg)a | −0.077 | 0.41 | 114 | |||||
| Positive symptomsb | 0.131 | 0.17 | 114 | |||||
| Negative symptomsc | 0.015 | 0.87 | 114 | |||||
| Depressive symptomsd | 0.341 | 0.001 | 98 | 0.024 | 0.8 | 114 | 2.35 | 0.009 |
| Anxiety symptomse | 0.202 | 0.06 | 90 | 0.089 | 0.35 | 111 | 0.8 | 0.21 |
| Mental Health | ||||||||
| Resiliencef | −0.074 | 0.49 | 90 | −0.204 | 0.03 | 110 | 0.92 | 0.18 |
| Mental well-beingg | −0.209 | 0.05 | 90 | −0.1 | 0.3 | 111 | −0.77 | 0.22 |
| Perceived Stressh | 0.21 | 0.05 | 89 | 0.119 | 0.21 | 111 | 0.64 | 0.26 |
| Overall cognitive dysfunctioni | −0.15 | 0.14 | 97 | 0.105 | 0.28 | 111 | −1.83 | 0.03 |
| Executive Functioningj | −0.096 | 0.35 | 99 | −0.06 | 0.53 | 114 | −0.26 | 0.4 |
| Physical Health | ||||||||
| Physical well-beingk | −0.292 | 0.005 | 90 | −0.251 | 0.008 | 111 | −0.3 | 0.38 |
| Physical comorbidityl | 0.275 | 0.006 | 99 | 0.062 | 0.52 | 114 | 1.57 | 0.06 |
| BMI | 0.144 | 0.16 | 99 | 0.29 | 0.002 | 112 | −1.08 | 0.14 |
| Biomarkers | ||||||||
| Fasting glucose (mg/dL) | 0.064 | 0.53 | 99 | 0.094 | 0.32 | 113 | −0.22 | 0.41 |
| Fasting insulin (mIU/L) | 0.266 | 0.009 | 95 | 0.231 | 0.02 | 106 | 0.25 | 0.4 |
| Hemoglobin A1C (%) | 0.13 | 0.23 | 85 | 0.13 | 0.21 | 95 | 0 | 0.5 |
| HOMA-IR | 0.26 | 0.01 | 95 | 0.227 | 0.02 | 106 | 0.24 | 0.4 |
Antipsychotic medication daily dosages were converted to WHO average daily doses based on published standards [WHO: Guidelines for ATC classification and DDD assignment, 2010 and WHO: Introduction to Drug Utilization Research, 2009]
As assessed with the Scale for the Assessment of Positive Symptoms (SAPS) total summary score of the four global domain scores (ranging from 0 to 20, higher scores indicating more positive symptoms)
As assessed with the Scale for the Assessment of Negative Symptoms (SANS) total summary score of the five global domain scores (ranging from 0 to 25, higher scores indicating more negative symptoms)
As assessed with the Calgary Depression Scale total score (ranging from 0 to 27, higher scores indicating more depressive symptoms)
As assessed with the Brief Symptom Inventory Anxiety Scale total score (ranging from 0 to 24, higher scores indicating more anxiety symptoms)
As assessed with the Connor Davidson Resilience 10-item Scale (ranging from 0 to 40, higher scores indicating greater overall resilience)
As assessed with the Short Form Health Survey (SF-36) Mental Composite score (computable range from −1.3 to 62.1, higher scores indicating better mental well-being)
As assessed with the Perceived Stress Scale (ranging from 0 to 40, higher scores indicating greater perceived stress)
As assessed with the Modified Telephone Interview for Cognitive Status (TICS-M) (ranging from 0 to 50, higher scores indicating better cognitive status)
As assessed with the Delis-Kaplan Executive Function System (reported as a standardized z-score, with higher values indicating better executive functioning)
As assessed with the Short Form Health Survey (SF-36) Physical Composite score (computable range from 1.7 to 76.3 from 0 to 100, higher scores indicating better physical well-being)
As assessed with the Cumulative Illness Rating Scale total score (ranging from 0 to 56, higher scores indicating a higher number or greater severity of physical comorbidities)
Abbreviations: CTQ = Childhood Trauma Questionnaire, Hemoglobin A1c = glycosylated hemoglobin, HOMA-IR = Homeostatic Model Assessment for Insulin Resistance