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. 2015 Oct 7;2015(10):CD010081. doi: 10.1002/14651858.CD010081.pub2

Summary of findings 9. Intense pulsed light compared with no treatment for hidradenitis suppurativa.

Intense pulsed light compared with no treatment for hidradenitis suppurativa
Patient or population: participants with hidradenitis suppurativa
 Settings: hospital‐based
 Intervention: intense pulsed light
 Comparison: no treatment
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) Number of participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
No treatment Intense pulsed light
Participant global assessment: satisfaction with treatment 
 Questionnaire
 Follow‐up: uncertain Study population RR 9.67 
 (2.01 to 46.43) 34
 (1 study) ⊕⊕⊝⊝
 low¹,²
0 per 1000 0 per 1000 
 (0 to 0)
Moderate
0 per 1000 0 per 1000 
 (0 to 0)
Participant global assessment: satisfaction with treatment ‐ axilla 
 Questionnaire
 Follow‐up: uncertain Study population RR 21.00 
 (1.37 to 322.28) 24
 (1 study) ⊕⊕⊝⊝
 low¹,²
0 per 1000 0 per 1000 
 (0 to 0)
Moderate
0 per 1000 0 per 1000 
 (0 to 0)
Participant global assessment: satisfaction with treatment ‐ groin 
 Questionnaire
 Follow‐up: uncertain Study population RR 5.00 
 (0.31 to 79.94) 8
 (1 study) ⊕⊕⊝⊝
 low¹,²
0 per 1000 0 per 1000 
 (0 to 0)
Moderate
0 per 1000 0 per 1000 
 (0 to 0)
Participant global assessment: satisfaction with treatment ‐ inframammary 
 Questionnaire
 Follow‐up: uncertain Study population RR 3.00 
 (0.24 to 37.67) 2
 (1 study) ⊕⊕⊝⊝
 low¹,²
0 per 1000 0 per 1000 
 (0 to 0)
Moderate
0 per 1000 0 per 1000 
 (0 to 0)
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: confidence interval; RR: risk ratio.
GRADE Working Group grades of evidence
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

¹Downgraded one level due to performance bias resulting from participants being unblinded, in the absence of a sham treatment for the control side.
 ²Downgraded one level for imprecision due to a small number of participants in only a single study.