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. 2015 Oct 7;2015(10):CD010081. doi: 10.1002/14651858.CD010081.pub2

NCT02421172.

Trial name or title Efficacy, Safety, and Pharmacokinetics Study of CJM112 in Hidradenitis Suppurativa Patients
Methods This is a phase 2, double‐blind, multicentre RCT with 3 parallel arms
Participants Participants are men and women 18 to 65 years of age (Hurley stages II to III)
Interventions
  • CJM112 high dose in period 1; placebo in period 2/placebo in period 1; CJM112 low dose in period 2/placebo in period 1; CJM112 high dose in period 2


CJM112 is a fully human IgG1 monoclonal antibody
Outcomes
  1. Proportion of responders measured by Physician Global Assessment (HS‐PGA) score; timing is not stated

Starting date April 2015
Contact information
Notes

BD: twice daily.
 DLQI: Dermatology Life Quality Index.
 HISERG: Hidradenitis Suppurativa European Research Group.
 HS: hidradenitis suppurativa.
 HS‐PGA: Hidradenitis Suppurativa Physician's Global Assessment.
 IgG1: immunoglobulin G1.
 Nd:YAG: neodymium‐doped yttrium aluminium garnet.
 PGA: Physician Global Assessment.
 OD: once daily.
 RCT: randomised controlled trial.