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. 2017 Mar 17;2017(3):CD010651. doi: 10.1002/14651858.CD010651.pub2

Summary of findings for the main comparison. Open thoracotomy compared to thoracostomy drainage for pleural empyema.

Open thoracotomy compared to thoracostomy drainage for pleural empyema
Patient or population: children with pleural empyema
 Intervention: open thoracotomy
 Comparison: thoracostomy drainage
Outcomes Anticipated absolute effects* (95% CI) Relative effect
 (95% CI) № of participants
 (studies) Quality of the evidence
 (GRADE) Comments
Thoracostomy drainage Open thoracotomy
Mortality
Follow‐up: up to 3 months after discharge
Risk in study population Not estimable 30
 (1 RCT) ⊕⊕⊕⊝
 MODERATE 1 No deaths occurred in either group.
Length of hospital stay (days)
Follow‐up: up to 3 months after discharge
The mean length of hospital stay in the control group was 15.4 days. The mean length of hospital stay in the intervention group was 5.9 days fewer (7.29 fewer to 4.51 fewer). 30
 (1 RCT) ⊕⊕⊕⊝
 MODERATE1  
Procedural complications
Follow‐up: up to 3 months after discharge
Risk in study population OR 0.10 
 (0.02 to 0.63) 30
 (1 RCT) ⊕⊕⊕⊝
 MODERATE 1  
600 per 1000 130 per 1000 
 (29 to 486)
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: confidence interval; OR: odds ratio; RCT: randomised controlled trial
GRADE Working Group grades of evidenceHigh quality: We are very confident that the true effect lies close to that of the estimate of the effect.
 Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
 Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect.
 Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect.

1Downgraded one level due to small sample size and only one study.