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. 2017 Mar 3;2017(3):CD004735. doi: 10.1002/14651858.CD004735.pub4

Comparison 2. Any planned birth versus expectant management (subgroup analysis by corticosteroid usage).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Neonatal infection 12 3652 Risk Ratio (M‐H, Fixed, 95% CI) 0.94 [0.68, 1.32]
1.1 Antenatal corticosteroids 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
1.2 No antenatal corticosteroids 6 495 Risk Ratio (M‐H, Fixed, 95% CI) 0.98 [0.48, 2.03]
1.3 Some antenatal corticosteroids 6 2850 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.64, 1.41]
1.4 Not known 1 307 Risk Ratio (M‐H, Fixed, 95% CI) 0.80 [0.25, 2.55]
2 Neonatal infection confirmed with positive culture 7 2939 Risk Ratio (M‐H, Fixed, 95% CI) 1.29 [0.74, 2.23]
2.1 Antenatal corticosteroids 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.2 No antenatal corticosteroids 3 259 Risk Ratio (M‐H, Fixed, 95% CI) 0.60 [0.18, 2.04]
2.3 Some antenatal corticosteroids 5 2680 Risk Ratio (M‐H, Fixed, 95% CI) 1.59 [0.85, 3.00]
3 Respiratory distress syndrome 12 3646 Risk Ratio (M‐H, Fixed, 95% CI) 1.29 [1.07, 1.56]
3.1 Antenatal corticosteroids 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.2 No antenatal corticosteroids 6 495 Risk Ratio (M‐H, Fixed, 95% CI) 1.32 [0.96, 1.83]
3.3 Some antenatal corticosteroids 6 2844 Risk Ratio (M‐H, Fixed, 95% CI) 1.28 [1.01, 1.63]
3.4 Not known 1 307 Risk Ratio (M‐H, Fixed, 95% CI) 1.27 [0.55, 2.94]
4 Caesarean section 12 3644 Risk Ratio (M‐H, Fixed, 95% CI) 1.26 [1.11, 1.44]
4.1 Antenatal corticosteroids 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.2 No antenatal corticosteroids 6 493 Risk Ratio (M‐H, Fixed, 95% CI) 1.43 [1.00, 2.06]
4.3 Some antenatal corticosteroids 6 2844 Risk Ratio (M‐H, Fixed, 95% CI) 1.27 [1.10, 1.47]
4.4 Not known 1 307 Risk Ratio (M‐H, Fixed, 95% CI) 0.91 [0.51, 1.61]
5 Chorioamnionitis 8 1358 Risk Ratio (M‐H, Fixed, 95% CI) 0.49 [0.33, 0.72]
5.1 Antenatal corticosteroids 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
5.2 No antenatal corticosteroids 4 398 Risk Ratio (M‐H, Fixed, 95% CI) 0.38 [0.22, 0.67]
5.3 Some antenatal corticosteroids 4 960 Risk Ratio (M‐H, Fixed, 95% CI) 0.61 [0.36, 1.06]
6 Endometritis 7 2980 Risk Ratio (M‐H, Fixed, 95% CI) 1.61 [1.00, 2.59]
6.1 Antenatal corticosteroids 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
6.2 No antenatal corticosteroids 2 185 Risk Ratio (M‐H, Fixed, 95% CI) 1.38 [0.32, 5.94]
6.3 Some antenatal corticosteroids 5 2795 Risk Ratio (M‐H, Fixed, 95% CI) 1.64 [0.99, 2.72]