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. 2017 Mar 3;2017(3):CD004735. doi: 10.1002/14651858.CD004735.pub4

Comparison 3. Any planned birth versus expectant management (subgroup analysis by gestational age for inclusion in trial).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Neonatal infection 12 3628 Risk Ratio (M‐H, Fixed, 95% CI) 0.93 [0.66, 1.30]
1.1 Greater than 34 weeks' gestation 5 2998 Risk Ratio (M‐H, Fixed, 95% CI) 0.71 [0.47, 1.07]
1.2 Less than 34 weeks' gestation 5 490 Risk Ratio (M‐H, Fixed, 95% CI) 1.61 [0.74, 3.50]
1.3 Not specified (wider span) 2 140 Risk Ratio (M‐H, Fixed, 95% CI) 2.00 [0.65, 6.18]
2 Neonatal infection confirmed with positive culture 7 2925 Risk Ratio (M‐H, Fixed, 95% CI) 1.24 [0.70, 2.21]
2.1 Greater than 34 weeks' gestation 4 2691 Risk Ratio (M‐H, Fixed, 95% CI) 1.07 [0.52, 2.20]
2.2 Less than 34 weeks' gestation 2 141 Risk Ratio (M‐H, Fixed, 95% CI) 1.67 [0.52, 5.35]
2.3 Not specified (wider span) 1 93 Risk Ratio (M‐H, Fixed, 95% CI) 1.53 [0.27, 8.75]
3 Respiratory distress syndrome 12 3622 Risk Ratio (M‐H, Fixed, 95% CI) 1.26 [1.05, 1.53]
3.1 Greater than 34 weeks' gestation 5 2992 Risk Ratio (M‐H, Fixed, 95% CI) 1.45 [1.10, 1.90]
3.2 Less than 34 weeks' gestation 5 490 Risk Ratio (M‐H, Fixed, 95% CI) 1.09 [0.84, 1.43]
3.3 Not specified (wider span) 2 140 Risk Ratio (M‐H, Fixed, 95% CI) 0.81 [0.27, 2.42]
4 Caesarean section 12 3620 Risk Ratio (M‐H, Fixed, 95% CI) 1.26 [1.11, 1.44]
4.1 Greater than 34 weeks' gestation 5 2992 Risk Ratio (M‐H, Fixed, 95% CI) 1.22 [1.05, 1.42]
4.2 Less than 34 weeks' gestation 5 488 Risk Ratio (M‐H, Fixed, 95% CI) 1.46 [1.08, 1.96]
4.3 Not specified (wider span) 2 140 Risk Ratio (M‐H, Fixed, 95% CI) 1.21 [0.45, 3.28]
5 Chorioamnionitis 8 1358 Risk Ratio (M‐H, Fixed, 95% CI) 0.49 [0.33, 0.72]
5.1 Greater than 34 weeks' gestation 3 847 Risk Ratio (M‐H, Fixed, 95% CI) 0.26 [0.12, 0.57]
5.2 Less than 34 weeks' gestation 4 418 Risk Ratio (M‐H, Fixed, 95% CI) 0.77 [0.45, 1.30]
5.3 Not specified (wider span) 1 93 Risk Ratio (M‐H, Fixed, 95% CI) 0.39 [0.15, 1.01]
6 Endometritis 7 2980 Risk Ratio (M‐H, Fixed, 95% CI) 1.61 [1.00, 2.59]
6.1 Greater than 34 weeks' gestation 3 2562 Risk Ratio (M‐H, Fixed, 95% CI) 0.37 [0.10, 1.40]
6.2 Less than 34 weeks' gestation 4 418 Risk Ratio (M‐H, Fixed, 95% CI) 2.23 [1.29, 3.84]