| Methods |
Quasi‐RCT |
| Participants |
165, first FS, mean age 20 months |
| Interventions |
Phenobarbitone 4 ‐ 5 per kilo, or no treatment |
| Outcomes |
RS @ 6 months |
| Notes |
Attrition 4, 2 per arm, unblinded study |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
High risk |
Alternate day allocation |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
None |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
4 of 165 lost but 39 of 88 stopped treatment |
| Selective reporting (reporting bias) |
Low risk |
Stated outcome objective met |
| Other bias |
Low risk |
No bias identified |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
None |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
None |
