Graziosi 2004

Methods	Consent for study obtained at time of diagnosis of early pregnancy failure. Randomised after at least one week of expectant management. Computer programme with block randomisation sequence. Stratification by previous vaginal birth; Gestational age < or > 10 weeks; centre.
Participants	154 women with ultrasound‐diagnosed early pregnancy failure ‐ either anembryonic pregnancy or fetal death at 6‐14 weeks. 6 centre study in Netherlands.
Interventions	Vaginal misoprostol 800 mcg; repeated after 24 hours if ultrasound indicated remaining tissue in the uterus. Curettage after 3 days if miscarriage hadn't occurred or was incomplete (n = 79) or suction curettage within a week of randomisation (n = 75).
Outcomes	Primary: complete evacuation. Secondary: side‐effects, pain and need for analgesia, intensity/duration of bleeding.
Notes	Of 241 eligible women, 87 (36%) declined to participate and chose curettage.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate