Ngoc 2004
| Methods | Randomised by opening sequentially numbered envelope ‐ prepared by computer‐generated code in blocks of 10. | |
| Participants | 200 women in Ho Chi Minh City, Vietnam, with non‐viable first trimester pregnancies (anembryonic or early fetal death) diagnosed by ultrasound; cervix closed. | |
| Interventions | Oral misoprostol 800 mcg (n = 100) versus vaginal misoprostol 800 mcg (n = 98). Women reviewed after 48 hours; if retained products present, they were given option of surgical evacuation or further review after another 5 days (when evacuation was performed if there were still products present). | |
| Outcomes | Primary: complete miscarriage without need for surgical evacuation. Secondary: adverse effects. | |
| Notes | 2 women lost to follow up. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment (selection bias) | Low risk | A ‐ Adequate |