1 Main outcomes |
12 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
1.1 Death at 1 to 2 years |
6 |
491 |
Risk Ratio (M‐H, Random, 95% CI) |
0.41 [0.18, 0.97] |
1.2 Death at 3 to 5 years |
5 |
768 |
Risk Ratio (M‐H, Random, 95% CI) |
0.72 [0.37, 1.44] |
1.3 Graft loss (all cause) at 1 to 2 years |
7 |
416 |
Risk Ratio (M‐H, Random, 95% CI) |
0.55 [0.30, 1.02] |
1.4 Graft loss (all cause) at 3 to 5 years |
5 |
768 |
Risk Ratio (M‐H, Random, 95% CI) |
0.73 [0.47, 1.14] |
1.5 Acute rejection, any episode (+ CNI) |
8 |
968 |
Risk Ratio (M‐H, Random, 95% CI) |
0.60 [0.43, 0.83] |
1.6 Acute rejection at 3 months (no CNI) |
3 |
85 |
Risk Ratio (M‐H, Random, 95% CI) |
0.70 [0.33, 1.46] |
1.7 Delayed graft function |
6 |
494 |
Risk Ratio (M‐H, Random, 95% CI) |
1.08 [0.70, 1.65] |
2 Other adverse effects |
6 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
2.1 Infection (all cause) |
1 |
108 |
Risk Ratio (M‐H, Random, 95% CI) |
1.38 [1.04, 1.82] |
2.2 Bacterial infection |
3 |
366 |
Risk Ratio (M‐H, Random, 95% CI) |
1.01 [0.76, 1.34] |
2.3 Viral infection (all cause) |
2 |
353 |
Risk Ratio (M‐H, Random, 95% CI) |
0.99 [0.72, 1.37] |
2.4 CMV infection |
3 |
332 |
Risk Ratio (M‐H, Random, 95% CI) |
1.52 [0.82, 2.84] |
2.5 HSV infection |
1 |
215 |
Risk Ratio (M‐H, Random, 95% CI) |
1.45 [0.89, 2.38] |
2.6 Fungal infection |
3 |
568 |
Risk Ratio (M‐H, Random, 95% CI) |
1.26 [0.33, 4.89] |
2.7 Malignancy or PTLD |
3 |
610 |
Risk Ratio (M‐H, Random, 95% CI) |
1.34 [0.52, 3.50] |
3 Serum creatinine |
5 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
3.1 3 months |
3 |
226 |
Mean Difference (IV, Random, 95% CI) |
‐0.93 [‐15.78, 13.93] |
3.2 1 year |
2 |
261 |
Mean Difference (IV, Random, 95% CI) |
‐6.22 [‐18.21, 5.76] |
3.3 3 to 4 years |
2 |
38 |
Mean Difference (IV, Random, 95% CI) |
‐21.10 [‐49.81, 7.61] |