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. 2014 Jan 23;2014(1):CD002840. doi: 10.1002/14651858.CD002840.pub3

da Cunha Filho 2002

Methods Parallel‐group design Participants randomised to groups using a random number table Allocation to groups was not concealed 13% drop outs at the end of the treatment phase Outcome assessors were not blinded to group allocation
Participants 7 participants in the EXP group and 8 participants in the CTL group Inclusion criteria: less than 6 weeks post stroke; hemiparetic stroke based on clinical examination or MRI, or both; significant gait deficit ‐ speed of no more than 36 m/min or FAC 0 to 2 (that is, needs assistance); sufficient cognition to participate in training (at least 21 on the MMSE); ability to stand and take at least 1 step with or without assistance; informed consent Exclusion criteria: any co‐morbidity or disability other than hemiparesis that would preclude gait training; recent myocardial infarction; any uncontrolled health condition for which exercise is contraindicated (e.g. diabetes); severe lower extremity joint disease or rheumatoid arthritis that would interfere with gait training; obesity (mass more than 110 kg)
Interventions Treated as inpatients for 5 x 20‐minute sessions per week for 2 to 3 weeks BWSTT (EXP): participants walked on a treadmill with up to 30% of their body weight supported using a harness Regular gait training (CTL): strengthening, functional and mobility activities
Outcomes Assessed at baseline and after treatment phase:
  • FAC

  • FIM ‐ locomotion score

  • fast walking speed over 5 metres using a gait aid and personal assistance, if required

  • walking endurance ‐ maximum distance walked in 5 minutes, using parallel bars if necessary

  • energy expenditure during gait

  • bike ergometer exercise test

Notes The rating of drop outs and the allocation concealment classification were changed based on correspondence from the trialist
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random number table
Allocation concealment (selection bias) High risk Inadequate (based on correspondence from the investigator)
Blinding of outcome assessment (detection bias) All outcomes High risk Not blinded (based on correspondence from the investigator)