Methods | Cross‐over group design Participants randomised to groups (group allocation in envelopes that were drawn by an independent person) 0% drop outs at the end of the first treatment phase Blinding of outcome assessors to group allocation | |
Participants | 15 participants allocated to the EXP then CTL order, and 15 participants allocated to the CTL then EXP order Inclusion criteria: first stroke; supratentorial lesion; 4 to 12 weeks post stroke; aged less than 75 years; not able to walk (FAC of 2 or less); able to sit unsupported on the edge of a bed; able to stand for at least 10 seconds with help; written informed consent Exclusion criteria: hip and knee extension deficit of more than 20 degrees; passive dorsiflexion of the affected ankle to less than a neutral position; severe impairment of cognition or communication; evidence of cardiac ischaemia, arrhythmia, decompression or heart failure; feeling of 'overexertion' or heart rate exceeding the age‐predicted maximum (i.e. 190 beats/minute minus age) during training; resting systolic blood pressure exceeding 200 mmHg at rest or dropping by more than 10 mmHg with increasing workload | |
Interventions | Treated as inpatients for 5 x 15 to 20‐minute sessions per week for 2 weeks
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Outcomes | This was an A‐B‐A (or B‐A‐B) design, so participants were assessed at baseline, at first cross‐over (2 weeks), at second cross‐over (4 weeks) and after treatment phase (6 weeks):
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Notes | The number of drop outs was changed based on correspondence with the trialists Trial treated as a parallel‐group design for this review by using the first treatment phase data only (that is baseline and first cross‐over data only) |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Lots with sealed opaque envelopes that were drawn by an independent person |
Allocation concealment (selection bias) | Low risk | Sealed opaque envelopes that were drawn by an independent person |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Outcome assessors were blinded to group assignment |