Comparison 8. Oxygenation index: INO versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Oxygenation index at 4 hours	1	50	Mean Difference (IV, Fixed, 95% CI)	‐11.8 [‐19.38, ‐4.22]
2 Oxygenation index at 12 hours	1	50	Mean Difference (IV, Fixed, 95% CI)	‐9.8 [‐18.59, ‐1.01]
3 Oxygenation index at 24 hours	5	368	Mean Difference (IV, Fixed, 95% CI)	‐2.31 [‐2.73, ‐1.89]
4 Oxygenation index at 48 hours	2	183	Mean Difference (IV, Random, 95% CI)	1.99 [‐10.40, 14.38]
5 Oxygenation index at 72 hours	2	245	Mean Difference (IV, Fixed, 95% CI)	‐3.48 [‐6.80, ‐0.15]