Comparison 3. Multinutrient supplements (oral, nasogastric routes, intravenous) versus control (by allocation concealment).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Mortality by end of study by risk of bias for allocation concealment	20	1385	Risk Ratio (M‐H, Fixed, 99% CI)	0.79 [0.55, 1.15]
1.1 Low risk of bias	10	682	Risk Ratio (M‐H, Fixed, 99% CI)	0.57 [0.32, 1.01]
1.2 Unclear risk of bias	7	462	Risk Ratio (M‐H, Fixed, 99% CI)	1.22 [0.65, 2.28]
1.3 High risk of bias	3	241	Risk Ratio (M‐H, Fixed, 99% CI)	0.78 [0.34, 1.79]
2 Participants with complications at end of study by risk of bias for allocation concealment	14	882	Risk Ratio (M‐H, Fixed, 99% CI)	0.69 [0.59, 0.81]
2.1 Low risk of bias	9	622	Risk Ratio (M‐H, Fixed, 99% CI)	0.78 [0.66, 0.92]
2.2 Unclear risk of bias	5	260	Risk Ratio (M‐H, Fixed, 99% CI)	0.38 [0.24, 0.61]
2.3 High risk of bias	0	0	Risk Ratio (M‐H, Fixed, 99% CI)	0.0 [0.0, 0.0]