NTR1676.

Trial name or title	TRUST (The Randomised Uterine Septum Transsection Trial)
Methods	Multicentre randomised controlled trial
Participants	Women with a septate uterus and a history of (recurrent) miscarriage, subfertility, or preterm birth
Interventions	Women will be randomised to septum resection or expectant management.
Outcomes	The primary outcome is live birth, defined as the birth of a living foetus beyond 24 weeks of gestational age. Secondary outcomes are ongoing pregnancy, clinical pregnancy, miscarriage, and complications following metroplasty. Based on retrospective studies, an improvement in the live birth rate is anticipated from 35% without surgery to 70% with surgery.
Starting date	October 2008
Contact information	Judith Rikken: j.f.rikken@amc.uva.nl
Notes	The sample size of this RCT is 68, and currently 43 women have been included. The expected final inclusion is December 2017.

RCT: randomised controlled trial