Wang 2009.
Methods | Prospective single‐centre RCT | |
Participants | n = 20 participants with ARDS | |
Interventions | Treatment: RM in BIPAP mode, performed 8‐hourly for 7 days or until weaning of MV Both groups: lung protective ventilation |
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Outcomes | EVLW, EVLWI after RM, respiratory mechanics, oxygenation parameters, CVP, plasma COP, dosage of corticosteroid and adrenergic drugs, 24‐hour net fluid balance at 0, 48 and 72 hours post randomization | |
Notes | Full article in Mandarin. Abstract only in English. Study author contacted 1 Dec 2014 and again in April 2015. Use of Chinese students to determine risk of bias | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Envelope method |
Allocation concealment (selection bias) | Unclear risk | Not stated |
Blinding (performance bias and detection bias) All outcomes | Low risk | Open‐label Blinding of treatment: no Blinding of assessor: not stated Blinding of data analysis: not stated |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Primary analysis was by intention‐to‐treat. |
Selective reporting (reporting bias) | Unclear risk | Information was insufficient to permit a judgement. |
Intention to treat | Low risk | Primary analysis was by intention‐to‐treat. |