Yang 2011.
| Methods | Prospective, single‐centre RCT | |
| Participants | n = 38. ARDS | |
| Interventions | Treatment: RM (PEEP 40 cm H2O, support pressure set to 0, FiO2 1.0 for 30 seconds), repeated 8‐hourly for 5 days Both groups: PSV, Pplat ≤ 30 cm H2O, minimum PEEP with FiO2 < 0.6 and PaO2 60‐80 mmHg |
|
| Outcomes | Oxygenation status for 5 days, lung injury indexes, adverse effects of RM and incidence of barotrauma | |
| Notes | Full article in Mandarin. Abstract only in English. Study author contacted 1 Dec 2014 | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | Envelope method |
| Allocation concealment (selection bias) | Low risk | "The envelope method" |
| Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not stated |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Information was insufficient to permit a judgement. |
| Selective reporting (reporting bias) | Unclear risk | Information was insufficient to permit a judgement. |
| Intention to treat | Unclear risk | Information was insufficient to permit a judgement. |
ABG = arterial blood gases; ACVC = assist control; APO = acute pulmonary oedema; ARDS = acute respiratory distress syndrome; BIPAP = bi‐level positive airway pressure; CO = cardiac output; COP = colloid osmotic pressure; COPD = chronic obstructive pulmonary disease; CPAP = continuous positive airway pressure; Crs = respiratory system compliance; CVP = central venous pressure; EELV = end‐expiratory lung volume; EVLW = extravascular lung water; EVLWI = extravascular lung water index; FiO2 = fraction of inspired oxygen; FRC = functional residual capacity; HR = heart rate; ICP = intracranial pressure; ICU = intensive care unit; IL = interleukin; LIP = lower inflection point; LISS = lung injury severity score; LOS = length of stay; LVEF = left ventricular ejection fraction; MAP = mean arterial pressure; MV = mechanical ventilation; NAECC = North American‐European Consensus Conference; PaO2 = arterial oxygen partial pressure; PaCO2 = arterial carbon dioxide partial pressure; PAP = pulmonary artery pressure; PBW = predicted body weight; PCV = pressure control ventilation; PCWP = pulmonary capillary wedge pressure; PEEP = positive end‐expiratory pressure; P/F = PaO2/FiO2; PIP = peak inspiratory pressure; Ppeak = peak pressure; Pplat = plateau pressure; PSV = pressure support ventilation; Qva/Qt = venous admixture; RCT = randomized controlled trial; RM = recruitment manoeuvre; RR = respiratory rate; SBP = systolic blood pressure; SpO2 = arterial oxygen saturation from pulse oximeter; TNF = tumour necrosis factor; VCV = volume‐cycled ventilation; Vd/Vt = dead space; VT = tidal volume.