DeMartini 1999.
Methods | Single center randomized controlled trial. | |
Participants | Intubated preterm infants | |
Interventions | The infants were randomly assigned to 1 of 2 dosage regimens.
All medication was given divided into 2 dosages per day. No patients were treated with any corticosteroids outside the study protocol. |
|
Outcomes | The primary outcomes were mortality, duration of mechanical ventilation and duration of oxygen dependence. Secondary outcomes were the occurrence of clinically suspected sepsis, NEC, hypertension, hyperglycemia and hypertriglyceridemia. No long‐term follow‐up was performed. |
|
Notes | Only published as abstract. The original investigator provided data on the incidence of BPD, defined as oxygen dependence at 36 weeks' PMA, combined with mortality at 36 weeks. No long‐term follow‐up performed. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No information. |
Allocation concealment (selection bias) | Low risk | By personal communication, no information on the methods. |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | By personal communication. |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | By personal communication. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Not specified in the abstract. |
Selective reporting (reporting bias) | Unclear risk | Unknown due to abstract form. |
Other bias | Unclear risk | Unknown due to abstract form. |