Welfringer 2011.
| Methods | RCT. Designed as a feasibility study Setting; Germany |
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| Participants | 30 participants with right‐hemisphere stroke, less than 6 months previously Inclusion criteria: had a diagnosis of right‐hemispheric stroke dated less than 6 months earlier; had no history of major psychiatric problems and no other co‐existing disease/disability; showed unilateral left visuospatial neglect symptoms as defined by a score of 54 or less on the Letter Cancellation Test; had no diagnosis of hemianopia; had sufficient sensory, physical and cognitive capacities to follow instructions for more than 30 minutes and no additional verbal‐memory deficits as defined by a percentage rank above 16 in the story recall sub‐test of the Wechsler‐Memory‐Scale‐Revised (WMS‐R); were aged between 20 and 75 years; were right‐handed; and had provided informed consent Experimental: n = 15; mean age 56.3 years (SD 11.2); mean time since stroke: 3.2 months (SD 1.5) Control: n = 15; mean age 57.3 years (SD 11.3): mean time since stroke: 3.4 months (SD 2.8) |
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| Interventions | Visuomotor‐imagery therapy (2 daily half‐hour sessions of visuomotor‐imagery therapy as an add‐on treatment over a period of 3 weeks; participants mentally practised positions and movements of the contralesional upper limb in a repetitive fashion and as vividly and intensively as possible; over the course of the 3‐week intervention period, they participated in 28 to 30 training sessions; a total of 4 positions and 6 sequences (simple and complex movements) were imagined, with 1 exercise being repeated up to 10 times per session) versus no supplementary intervention All participants received standardised rehabilitation therapies including 45 minutes of exploration training 4 times per week For analysis of bottom‐up and top‐down rehabilitation approaches this review coded the experimental condition as top‐down |
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| Outcomes | Neglect tests: Bells Cancellation test; drawing tasks; text‐reading task Representation tests: test of mental representation of left side of body Arm function texts: sensation of left arm; Action Research Arm Test For analyses within this review we used: neglect ‐ Bells Cancellation Test |
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| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment (selection bias) | Low risk | Blocked randomisation, in blocks of 10; computer‐generated sequence, delivered by person independent of intervention |
| Blinding of outcome assessment (detection bias) All outcomes | Low risk | States: "Outcome measures were assessed by a blinded tester." |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up |
| Free of systematic differences in baseline characteristics of groups compared? | Low risk | No differences noted between groups |
| Did authors adjust for baseline differences in their analyses? | Low risk | Not necessary |