Skip to main content
. 2013 Jul 1;2013(7):CD003586. doi: 10.1002/14651858.CD003586.pub3

Welfringer 2011.

Methods RCT. Designed as a feasibility study
Setting; Germany
Participants 30 participants with right‐hemisphere stroke, less than 6 months previously
Inclusion criteria: had a diagnosis of right‐hemispheric stroke dated less than 6 months earlier; had no history of major psychiatric problems and no other co‐existing disease/disability; showed unilateral left visuospatial neglect symptoms as defined by a score of 54 or less on the Letter Cancellation Test; had no diagnosis of hemianopia; had sufficient sensory, physical and cognitive capacities to follow instructions for more than 30 minutes and no additional verbal‐memory deficits as defined by a percentage rank above 16 in the story recall sub‐test of the Wechsler‐Memory‐Scale‐Revised (WMS‐R); were aged between 20 and 75 years; were right‐handed; and had provided informed consent
Experimental: n = 15; mean age 56.3 years (SD 11.2); mean time since stroke: 3.2 months (SD 1.5)
Control: n = 15; mean age 57.3 years (SD 11.3): mean time since stroke: 3.4 months (SD 2.8)
Interventions Visuomotor‐imagery therapy (2 daily half‐hour sessions of visuomotor‐imagery therapy as an add‐on treatment over a period of 3 weeks; participants mentally practised positions and movements of the contralesional upper limb in a repetitive fashion and as vividly and intensively as possible; over the course of the 3‐week intervention period, they participated in 28 to 30 training sessions; a total of 4 positions and 6 sequences (simple and complex movements) were imagined, with 1 exercise being repeated up to 10 times per session) versus no supplementary intervention
All participants received standardised rehabilitation therapies including 45 minutes of exploration training 4 times per week
For analysis of bottom‐up and top‐down rehabilitation approaches this review coded the experimental condition as top‐down
Outcomes Neglect tests: Bells Cancellation test; drawing tasks; text‐reading task
Representation tests: test of mental representation of left side of body
Arm function texts: sensation of left arm; Action Research Arm Test
For analyses within this review we used: neglect ‐ Bells Cancellation Test
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk Blocked randomisation, in blocks of 10; computer‐generated sequence, delivered by person independent of intervention
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk States: "Outcome measures were assessed by a blinded tester."
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No loss to follow‐up
Free of systematic differences in baseline characteristics of groups compared? Low risk No differences noted between groups
Did authors adjust for baseline differences in their analyses? Low risk Not necessary