Borenstein 1981.

Methods	RCT, double blind Randomisation by coded numbers, although procedure not explained Disability outcome measured by clinical neurological score, Mathew Scale
Participants	Participants with an acute ischaemic stroke within 24 hours
Interventions	Dextran in 5% dextrose versus Hartmann's (control) for 72 hours
Outcomes	Death Change in Mathew score
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomisation procedure not explained
Allocation concealment (selection bias)	Unclear risk	Rule for allocating participants to category and subsequent concealment of allocation not explained
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double blind
Blinding of outcome assessment (detection bias) All outcomes	Low risk	—
Incomplete outcome data (attrition bias) All outcomes	Low risk	Data fully reported
Selective reporting (reporting bias)	Low risk	—
Other bias	Low risk	—