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. 2012 Mar 14;2012(3):CD005315. doi: 10.1002/14651858.CD005315.pub2

Comparison 3. Music versus blank tape / headphones only.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Anxiety 10   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
1.1 Pre‐procedural anxiety 4 361 Std. Mean Difference (IV, Random, 95% CI) ‐0.82 [‐1.03, ‐0.60]
1.2 Procedural anxiety 3 183 Std. Mean Difference (IV, Random, 95% CI) ‐0.12 [‐0.47, 0.23]
1.3 Post‐operative anxiety 3 220 Std. Mean Difference (IV, Random, 95% CI) ‐0.04 [‐0.52, 0.44]
1.4 ICU anxiety 1 64 Std. Mean Difference (IV, Random, 95% CI) 0.17 [‐0.32, 0.66]
2 Heart rate 8 543 Mean Difference (IV, Random, 95% CI) 0.40 [‐1.02, 1.82]
3 Blood pressure 8   Mean Difference (IV, Random, 95% CI) Subtotals only
3.1 Systolic 7 533 Mean Difference (IV, Random, 95% CI) ‐0.40 [‐2.48, 1.67]
3.2 Diastolic 6 478 Mean Difference (IV, Random, 95% CI) ‐0.35 [‐2.08, 1.39]
3.3 Arterial 1 30 Mean Difference (IV, Random, 95% CI) 4.0 [‐5.33, 13.33]
4 Respiration rate: with choice of outcomes 2   Mean Difference (IV, Random, 95% CI) Subtotals only
4.1 Post‐operative period for Ikonomidou 2004 and final scores (both studies) 2 119 Mean Difference (IV, Random, 95% CI) ‐1.72 [‐1.00, ‐0.44]
4.2 Post‐operative period for Ikonomidou 2004 and change score for Lee 2005 2 119 Mean Difference (IV, Random, 95% CI) ‐2.48 [‐3.85, ‐1.11]
4.3 Pre‐operative period for Ikonomidou 2004 and final scores (both studies) 2 119 Mean Difference (IV, Random, 95% CI) ‐0.92 [‐1.92, 0.09]
4.4 Pre‐operative period for Ikonomidou 2004 and change scores for Lee 2005 2 119 Mean Difference (IV, Random, 95% CI) ‐2.09 [‐4.51, 0.34]
5 Skin conductance 2   Std. Mean Difference (IV, Random, 95% CI) Totals not selected
6 Stress hormones 3   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
6.1 Cortisol 3 216 Std. Mean Difference (IV, Random, 95% CI) ‐0.32 [‐0.73, 0.09]
6.2 Epinephrine 2 123 Std. Mean Difference (IV, Random, 95% CI) ‐0.02 [‐0.38, 0.33]
6.3 Norepinephrine 2 123 Std. Mean Difference (IV, Random, 95% CI) ‐0.08 [‐0.44, 0.27]
6.4 Adrenocorticotropic hormone (ACTH) 1 30 Std. Mean Difference (IV, Random, 95% CI) ‐0.44 [‐1.17, 0.28]