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. 2010 Apr 14;2010(4):CD006432. doi: 10.1002/14651858.CD006432.pub2

Platz 2001

Methods Random allocation to 1 of 2 groups, with blocked randomisation according to side of stroke Details of allocation concealment not stated
Participants 14 participants Inclusion criteria: CT‐proven stroke in middle cerebral artery territory, sub‐acute phase, clinically complete or almost complete recovery from hemiparesis, no cognitive impairment Note: it is unclear whether or not these were pre‐stated inclusion criteria, or whether these criteria are descriptors of the included participants written following patient assessment
Interventions Group 1: unilateral training Group 2: bilateral training Each group completed 3 training tasks (fast and accurate aiming movements, fast tapping movements with index finger, picking up and placing small wooden sticks) Each participant completed training comprising of 10 practice blocks, each lasting 2.5 minutes Tasks were completed in a repetitive way and serial order Total training time was approximately 30 minutes per session, performed on 5 consecutive weekdays Training was supervised by an occupational therapist
Outcomes Secondary outcome: motor impairment ‐ temporal outcomes: total movement time (ms), MT/first phase, MT/second phase, MT coefficient of variation (total movement time selected); spatial outcomes: spatial error (mm), spatial error/first phase (spatial error selected) All outcomes assessed for aiming movements during single task and dual task Outcome data for single task aiming movement used for analysis
Notes Data extracted comprised least square means Standard deviation for outcome not provided Baseline standard deviation used as estimated value for both groups and imputed for the analysis Number of participants in each group not stated; assumed 50% (7 participants) assigned to each group 14 healthy controls were also recruited; numbers not included in participant numbers or in analysis Movement time and spatial error data inverted for analysis (multiplied by ‐1)
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk Not stated
Blinding of outcome assessor? Unclear risk Not stated
Intention to treat analysis? Unclear risk Not stated
Baseline similarity Low risk Reported as comparable with regards to age, gender, cortical versus subcortical/basal ganglia stroke and severity of residual paresis